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Neurogenin3 Antibody
Purified Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9Y4Z2 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | monoclonal |
| Isotype | IgG2a,k |
| Clone/Animal Names | 1800CT113.128.46 |
| Calculated MW | 23077 Da |
| Gene ID | 50674 |
|---|---|
| Other Names | Neurogenin-3, NGN-3, Class A basic helix-loop-helix protein 7, bHLHa7, Protein atonal homolog 5, NEUROG3, ATOH5, BHLHA7, NGN3 |
| Target/Specificity | This Neurogenin3 antibody is generated from a mouse immunized with a recombinant protein between 1-214 amino acids from human Neurogenin3. |
| Dilution | WB~~1:4000 E~~Use at an assay dependent concentration. |
| Format | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Neurogenin3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NEUROG3 |
|---|---|
| Synonyms | ATOH5, BHLHA7, NGN3 |
| Function | Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types (By similarity). |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Acts as a transcriptional regulator. Together with NKX2- 2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types (By similarity).
References
Ravassard P.,et al.Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
del Bosque-Plata L.,et al.Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 429:375-381(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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